General Information

  • ID:  hor002500
  • Uniprot ID:  NA
  • Protein name:  Caerulein
  • Gene name:  NA
  • Organism:  Macropus eugenii
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EQDYTGWMDF
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T4 Tyrosine amide;T10 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Play a role in the protection of pouch young;contract smooth muscle and enhances the proliferation of splenocytes
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002500_AF2.pdbhor002500_ESM.pdb

Physical Information

Mass: 145207 Formula: C58H74N12O20S
Absent amino acids: ACHIKLNPRSV Common amino acids: D
pI: 3.38 Basic residues: 0
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: -126 Boman Index: -2390
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: 5902 Extinction Coefficient cystines: 6990
Absorbance 280nm: 776.67

Literature

  • PubMed ID:  15654881
  • Title:  An Immunomodulator Used to Protect Young in the Pouch of the Tammar Wallaby, Macropus Eugenii